Related Experiment Video

Updated: Aug 6, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
07:02

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

Published on: September 14, 2010

Disseminated Sporothix schenckii in a patient with AIDS

S Hardman1, I Stephenson, D R Jenkins

  • 1Department of Clinical Microbiology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester, UK. susanhardman@hotmail.com

The Journal of Infection
|October 19, 2005
PubMed

Insights

Sporothrix schenckii meningitis is a rare complication in individuals with acquired immunodeficiency syndrome (AIDS). This case highlights diagnostic challenges and treatment failure in a UK patient with AIDS and S. schenckii meningitis.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Neurology

Background:

  • Sporothrix schenckii is a dimorphic fungus causing cutaneous infections.
  • Disseminated sporotrichosis is rare, primarily affecting immunodeficient individuals.
  • Meningitis due to S. schenckii is an exceptionally rare complication.

Observation:

  • The study presents the first reported case of S. schenckii meningitis in the UK.
  • The patient had acquired immunodeficiency syndrome (AIDS).
  • Clinical presentation included meningoencephalitis, hydrocephalus, and multiple cutaneous lesions.

Findings:

  • Diagnosis required isolation of S. schenckii from cerebrospinal fluid (CSF) and skin.
  • The patient's condition did not improve with therapy.
  • This case underscores the diagnostic difficulties associated with S. schenckii meningitis.

Implications:

  • Highlights the importance of considering rare fungal infections in immunocompromised patients.
  • Emphasizes the need for prompt diagnosis and effective treatment strategies for S. schenckii meningitis.
  • Contributes to understanding the clinical spectrum of sporotrichosis in AIDS patients.

More Related Videos

Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases03:22

Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases

Published on: March 1, 2024

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients05:26

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...