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Updated: Aug 6, 2026

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
Published on: December 28, 2017
Candida glabrata fungemia cured by antibiotic-lock therapy: case report and short review
A Angel-Moreno1, M Boronat, M Bolaños
1Unidad de Enfermedades Infecciosas y Medicina Tropical, Hospital Universitario Insular, Las Palmas de Gran Canaria, Spain.
Abstract:
Catheter removal is now the standard recommendation of catheter-related fungemia even when tunneled devices are used. However, in the clinical practice, this procedure is not always without risks. Antibiotic-lock technique can resolve many cases of catheter-related bacteraemia, but cure of catheter-related candidemia by this method has been attempted in very few instances, reviewed in this article. Herein, we report a case of non-complicated Candida glabrata fungemia related to a Hickman catheter used for parenteral nutrition, cured with intraluminal amphotericin B in addition to systemic therapy. This case demonstrates that 'antifungal-lock therapy' can be effectively used in selected cases of catheter-related candidemia.
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