Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Plasma cell leukaemia].

C Rodriguez1, J-C Pont, I Gouin-Thibault

  • 1Laboratoire d'hématologie, Groupe hospitalier Charles Foix Jean Rostand, Ivry Sur Seine.

Annales De Biologie Clinique
|October 19, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correlation between molecular and histopathological diagnoses of B cell lymphomas in bone marrow biopsy and aspirates.

Journal of clinical pathology·2009
Same author

Is sclerosing angiomatoid nodular transformation (SANT) of the splenic red pulp identical to inflammatory pseudotumour? Report of 16 cases.

Histopathology·2008
Same author

Primary mediastinal anaplastic alk-1-positive large-cell lymphoma of T/NK-cell type expressing CD20.

Virchows Archiv : an international journal of pathology·2007
Same author

Initial lesions of classical Hodgkin's lymphoma of the nodular sclerosis type.

Arkhiv patologii·2006
Same author

Marginal zone lymphoma of both spleen and kidney displaying transformation into large B-cell lymphoma.

International urology and nephrology·2006
Same author

Are multicentric Castleman's disease with cutaneous plasmacytosis and systemic plasmacytosis the same entity?

Histopathology·2006
Same journal

[The role of the heart-on-a-chip to drug evaluation].

Annales de biologie clinique·2026
Same journal

A morphology-driven proof-of-concept study linking interphase nuclear abnormalities to dicentric-mediated genomic instability.

Annales de biologie clinique·2026
Same journal

Analytical validation and clinical concordance of Diazyme free light chain assays on the Cobas® platform compared with Freelite™.

Annales de biologie clinique·2026
Same journal

Small-cell secondary plasma cell leukemia mimicking low-grade B-cell lymphoma.

Annales de biologie clinique·2026
Same journal

[Multiple myeloma and analytical discrepancy in serum free light chain assay: a case report].

Annales de biologie clinique·2026
Same journal

[Summary of the 34th National Conference of the National College of Hospital Biochemistry].

Annales de biologie clinique·2026
See all related articles

This case study details an 83-year-old woman with primary plasma cell leukaemia. Treatment with thalidomide and dexamethasone led to remission, showing no circulating plasma cells after three weeks.

Area of Science:

  • Hematology
  • Oncology
  • Clinical Medicine

Background:

  • Primary plasma cell leukaemia (PPCL) is a rare and aggressive plasma cell dyscrasia.
  • Diagnosis typically involves a high absolute plasma cell count in peripheral blood.

Observation:

  • An 83-year-old female presented with PPCL, characterized by an absolute plasma cell count of 53 Giga/L.
  • The patient exhibited clinical symptoms consistent with advanced plasma cell malignancy.

Findings:

  • A treatment regimen combining thalidomide and dexamethasone for 5 days, followed by thalidomide monotherapy, resulted in complete remission.
  • Post-treatment evaluation showed no circulating plasma cells after 3 weeks, indicating significant therapeutic response.

Implications:

Related Experiment Videos

  • This case highlights the efficacy of thalidomide and dexamethasone in managing primary plasma cell leukaemia.
  • The findings suggest that this combination therapy can achieve rapid and effective disease control in elderly patients.