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Updated: Aug 15, 2026

Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
Published on: March 7, 2025
[Phenotypic and functional analysis of T lymphocytes in cancer patients]
Cécile Badoual1, Benoît Vingert, Nour Agueznay
1INSERM U 255, Institut Biomédical des Cordeliers, Université Paris 5.
Abstract:
In preclinical tumor model and in human cancer, tumor antigen specific T lymphocytes play a key role in the control of tumor development. Nevertheless in numerous cases, the infiltrating tumor T cells do not seem to influence the clinical progression of the tumor. A better phenotypic and functional characterization of T cells in close contact with tumor associated with a comprehensive analysis of tumor evasion mechanism to the host response should lead to an optimization of cancer immunotherapy protocols.
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