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Updated: Aug 15, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[Prevention and treatment of atrial fibrillation after cardiac surgery]
G Sleilaty1, A Sarkis, P Achouh
1Université Saint-Joseph, hôpital Hôtel-Dieu, Beyrouth (Liban).
Insights
Postoperative atrial fibrillation (POAF) remains common after cardiac surgery, with unknown causes. While some drugs and pacing reduce POAF incidence, the optimal treatment strategy is still undefined.
Area of Science:
- Cardiology
- Cardiac Surgery
- Anesthesiology
Context:
- Postoperative atrial fibrillation (POAF) incidence remains high following cardiac surgery.
- Despite advancements in anesthetic, pharmacological, and surgical techniques, the precise mechanisms of POAF are not fully understood.
- POAF significantly increases hospital length of stay and associated costs.
Purpose:
- To review current understanding and management strategies for POAF in cardiac surgery.
- To evaluate the efficacy of various interventions in preventing and treating POAF.
- To identify gaps in knowledge and define the optimal therapeutic approach.
Summary:
- Beta-blockers, amiodarone, and atrial pacing have demonstrated reductions in POAF incidence compared to placebo.
- Amiodarone and propafenone are effective in converting established POAF to normal sinus rhythm.
- The optimal pharmacological treatment for POAF remains to be determined.
Impact:
- Highlights the significant clinical and economic burden of POAF.
- Underscores the need for further research into POAF mechanisms and treatment.
- Informs clinical decision-making regarding POAF prevention and management protocols.
Abstract:
The incidence of postoperative atrial fibrillation in cardiac surgery is still high despite major advances in anesthetic, pharmacological and surgical techniques. Its precise mechanism is still totally unknown. Postoperative atrial fibrillation increases length of stay as well as hospital costs. Rate of postoperative atrial fibrillation spontaneous conversion is high. Several protocols have been developed for prevention and/or treatment of postoperative atrial fibrillation. Beta-blockers, amiodarone and atrial pacing reduce.atrial fibrillation incidence as compared to placebo. On the other hand, amiodarone and propafenone achieve a high conversion rate of installed postoperative atrial fibrillation. However, among many pharmacological options, the best treatment is still to be defined.
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