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Updated: Aug 6, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
[Late occlusion of the subclavian artery proximal to mammary bypass]
S Fukui1, E Chelbi, N Paraskevas
1Service de Chirurgie Vasculaire, Foundation-Hôpital Saint-Joseph, Paris. sumio_fukui@yahoo.com
Insights
Left internal mammary artery bypasses are effective, but proximal subclavian artery occlusion can cause myocardial ischemia. Re-implantation relieved symptoms, highlighting the need for surveillance of bypass grafts.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Vascular Surgery
Background:
- Internal mammary artery (IMA) grafts are preferred for coronary artery bypass grafting (CABG) due to resistance to atherosclerosis.
- Proximal subclavian artery (SCA) lesions can compromise flow in IMA grafts used for coronary revascularization.
Observation:
- Two patients developed left SCA occlusion years after left IMA to anterior interventricular artery bypass.
- Myocardial ischemia was detected via scintigraphy in one patient and presented as exertional angina in the upper limb in the other.
Findings:
- Re-implantation of the occluded SCA into the common carotid artery successfully resolved myocardial ischemia in both patients.
- Proximal SCA stenosis or occlusion poses a risk to the myocardial territory revascularized by an IMA graft.
Implications:
- While IMA grafts are durable, the proximal SCA feeding the graft is susceptible to atherosclerotic disease.
- Regular clinical evaluation and ultrasound surveillance are crucial for detecting proximal SCA lesions in patients with IMA bypass grafts.
Abstract:
We report the cases of two patients with an occlusion of the left subclavian artery several years after left internal mammary bypass of the anterior interventricular artery. The effect on the myocardium was only apparent after scintigraphy in one case, and was clinical in the second with angina pain on exertion of the upper limb. Re-implantation of the subclavian artery in the common carotid relieved the signs of myocardial ischaemia. While the internal mammary artery is the conduit of choice for coronary revascularisation because it is not affected by atheromatous lesions, this does apply to the proximal subclavian artery. Stenosis or occlusion here can entail ischaemia in the revascularised myocardial territory. Regular clinical and ultrasound surveillance can detect these lesions.
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