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Anticonvulsant-induced chronic pancreatitis. A case report
R Pezzilli1, P Billi, R Melandri
1Servizio di Pronto Soccorso, Ospedale S. Orsola, Bologna, Italy.
The Italian Journal of Gastroenterology
|June 1, 1992
Abstract:
We report the case of a young man suffering from epilepsy who developed chronic calcified pancreatitis after ten years of therapy with the anticonvulsant drugs carbamazepine and phenytoin. Long-term anticonvulsant drug therapy may have a contributory role in the development of chronic pancreatitis by chronic stimulation of cytochromes P-450.