Related Experiment Video

Updated: Aug 15, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

[The child from families with type 1 diabetes]

Renata Wasikowa1, Dorota Suchańska, Danuta Suchańska

  • 1Katedra i Klinika Endokrynologii i Diabetologii Wieku Rozwojowego AM we Wrocłlawiu.

Endokrynologia, Diabetologia I Choroby Przemiany Materii Wieku Rozwojowego : Organ Polskiego Towarzystwa Endokrynologow Dzieciecych
|October 20, 2005
PubMed

Insights

Type 1 diabetes poses a significant teratogenic risk, increasing congenital defect likelihood by 3-5 fold. Hyperglycemia is the primary cause, leading to various birth defects and neonatal complications.

Area of Science:

  • Endocrinology
  • Teratology
  • Neonatology

Context:

  • Type 1 diabetes is a significant risk factor for congenital anomalies.
  • Genetic predisposition plays a role in Type 1 diabetes development.
  • Maternal hyperglycemia during pregnancy is a key teratogenic factor.

Purpose:

  • To highlight the teratogenic risks associated with Type 1 diabetes.
  • To outline the spectrum of congenital defects and neonatal complications.
  • To emphasize the need for continuous medical surveillance for high-risk infants.

Summary:

  • Type 1 diabetes is linked to a 3-5 fold increased risk of congenital defects.
  • Central nervous system, skeletal, urinary, and digestive systems are commonly affected.
  • Neonatal complications include macrosomia, hypocalcemia, hypertrophic cardiomyopathy, and respiratory distress.

Impact:

  • Informs healthcare providers about the critical need for glycemic control in diabetic pregnancies.
  • Underscores the importance of prenatal screening and monitoring for congenital anomalies.
  • Guides management strategies for infants born to mothers with Type 1 diabetes.

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