Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple sclerosis in childhood.

F Hanefeld1

  • 1Department of Pediatrics and Pediatric Neurology, University of Göttingen, Germany.

Current Opinion in Neurology and Neurosurgery
|June 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intrathecal IgM synthesis in pediatric MS is not a negative prognostic marker of disease progression: quantitative versus qualitative IgM analysis.

Multiple sclerosis (Houndmills, Basingstoke, England)·2010
Same author

Paediatric and adult multiple sclerosis: age-related differences and time course of the neuroimmunological response in cerebrospinal fluid.

Multiple sclerosis (Houndmills, Basingstoke, England)·2009
Same author

Chronic relapsing opsoclonus-myoclonus syndrome: combination of cyclophosphamide and dexamethasone pulses.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2007
Same author

Proton MRS of a child with Sandhoff disease reveals elevated brain hexosamine.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2007
Same author

High seroprevalence of Epstein-Barr virus in children with multiple sclerosis.

Neurology·2006
Same author

Baló's concentric sclerosis associated with primary human herpesvirus 6 infection.

Journal of neurology, neurosurgery, and psychiatry·2005
Same journal

Neuropharmacology.

Current opinion in neurology and neurosurgery·1993
Same journal

Disorders of the spinal cord and cauda equina.

Current opinion in neurology and neurosurgery·1993
Same journal

Autonomic disorders.

Current opinion in neurology and neurosurgery·1993
Same journal

Molecular and cell biology of addiction.

Current opinion in neurology and neurosurgery·1993
Same journal

Molecular mechanisms of trauma-induced neuronal degeneration.

Current opinion in neurology and neurosurgery·1993
Same journal

Excitatory amino acid receptors and epilepsy.

Current opinion in neurology and neurosurgery·1993
See all related articles

Childhood multiple sclerosis (MS) is increasingly diagnosed. This study in Göttingen examines 20 pediatric MS patients, highlighting the research potential of early-onset neurological conditions.

Area of Science:

  • Neurology
  • Pediatrics
  • Immunology

Background:

  • Multiple sclerosis (MS) is a chronic autoimmune disease typically diagnosed in adulthood.
  • An increasing trend of pediatric-onset MS (children and adolescents) is being observed globally.
  • Early-onset MS presents unique diagnostic and management challenges compared to adult forms.

Purpose of the Study:

  • To describe the occurrence and characteristics of multiple sclerosis in childhood.
  • To present preliminary findings from an ongoing study of pediatric MS patients in Göttingen.
  • To emphasize the significance of childhood MS as a model for neurological research.

Main Methods:

  • Retrospective and prospective data collection on pediatric MS patients.
  • Clinical assessment and diagnostic criteria for childhood MS.

Related Experiment Videos

  • Analysis of patient demographics, clinical presentation, and disease course.
  • Main Results:

    • The study includes data from 20 pediatric patients diagnosed with MS.
    • Observations on the increasing incidence of MS with onset before puberty.
    • Initial findings suggest distinct patterns in childhood MS compared to adult-onset MS.

    Conclusions:

    • Childhood multiple sclerosis is a growing concern requiring further investigation.
    • Pediatric MS offers a valuable research platform for understanding disease mechanisms and therapeutic interventions.
    • Early diagnosis and management are crucial for improving outcomes in young MS patients.