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Updated: Aug 15, 2026

08:35
Human Pancreatic Islet Isolation: Part II: Purification and Culture of Human Islets
Published on: May 26, 2009
Improvement of islet culture with sericin
Akiko Ogawa1, Satoshi Terada, Takanori Kanayama
1Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui, 3-9-1, Bunkyo, Fukui 910-8507, Japan.
Journal of Bioscience and Bioengineering
|October 20, 2005
Abstract:
Islet transplantation is a promising treatment for diabetes. Serum is a necessary supplement in islet cultures, but it has various disadvantages including the risk of contamination by several pathogens. Results of this study suggest that sericin is a useful alternative supplement. Sericin accelerated the proliferation of the rat insulinoma cell line RIN-5F and improved the serum-free culture of rat islets.

