Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biological fixation of endosseous implants.

M Franchi1, M Fini, D Martini

  • 1Dipartimento di Scienze Anatomiche Umane e Fisiopatologia dell'Apparato Locomotore, Università di Bologna, Via Irnerio 48, 40126 Bologna, Italy. marcofranchi@inwind.it

Micron (Oxford, England : 1993)
|October 20, 2005
PubMed
Summary

Bone chips and newly formed trabecular bone create a biological anchorage for titanium implants, ensuring stability. This network facilitates osseointegration and bone turnover around various implant surfaces within two weeks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early multimodal behavioral cues in autism: a micro-analytical exploration of actions, gestures and speech during naturalistic parent-child interactions.

International journal of clinical and health psychology : IJCHP·2026
Same author

Indications for haematopoietic cell transplantation and CAR-T for haematological diseases, solid tumours and immune disorders: 2025 EBMT practice recommendations.

Bone marrow transplantation·2025
Same author

CC486 as a safe and effective bridge to transplant in MDS-del5q with transfusion-dependent anemia following lenalidomide relapse: A case report.

Current research in translational medicine·2025
Same author

Feasibility of energy dispersive X-ray fluorescence for quantitative prediction of elemental profile in untreated bovine colostrum.

Journal of dairy science·2025
Same author

The use of MSCs in steroid-refractory acute GvHD in Europe: a survey from the EBMT cellular therapy & immunobiology working party.

Bone marrow transplantation·2025
Same author

Climate change and occupational health and safety. Risk of injuries, productivity loss and the co-benefits perspective.

Environmental research·2025

Area of Science:

  • Biomaterials Science
  • Orthopedic Surgery
  • Histology

Background:

  • Primary implant stability relies on mechanical fixation.
  • Biological anchorage is crucial for long-term osseointegration during healing.

Purpose of the Study:

  • To investigate the histological aspects of biological fixation around titanium screws.
  • To evaluate the role of bone chips and early bone formation in implant anchorage.

Main Methods:

  • Forty-eight titanium screws with varied surfaces (smooth, plasma sprayed, sand blasted) were implanted in sheep tibiae and femurs.
  • Histological analysis using light microscopy and Scanning Electron Microscopy (SEM) was performed at 1 hour, 14 days, and 90 days post-implantation.

Main Results:

Related Experiment Videos

  • At 1 hour, the implant-bone gap contained blood clot and bone chips.
  • By 14 days, new trabecular bone enveloped bone chips, forming a biological fixation network.
  • At 90 days, mature lamellar bone replaced earlier structures, with marrow spaces present.

Conclusions:

  • Trabecular bone and bone chips form a crucial three-dimensional network for biological implant fixation within two weeks.
  • Host bone chips may promote peri-implant osteogenesis.
  • Peri-implant marrow spaces facilitate bone turnover around the implant.