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A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

Appropriate invasive and conservative strategies for patients with non-ST elevation acute coronary syndromes

Sameer K Mehta1, James A de Lemos

  • 1The Donald W Reynolds Cardiovascular Clinical Research Center and the Division of Cardiology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9047, USA.

Current Opinion in Cardiology
|October 20, 2005
PubMed

Insights

This review examines recent advances in managing acute coronary syndromes, focusing on early invasive strategies for elderly patients, low-molecular-weight heparin use, and intensive lipid-lowering treatments. Evidence on these controversial topics is critically evaluated.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Acute coronary syndromes (ACS) management is evolving.
  • Controversies exist regarding optimal treatment strategies.

Purpose of the Study:

  • To review recent developments in three controversial areas of ACS management.
  • To evaluate evidence on early invasive strategies, low-molecular-weight heparin, and intensive lipid-lowering therapy in ACS.

Main Methods:

  • Literature review of recent clinical trials and evidence.
  • Critical evaluation of data regarding specific treatment modalities.

Main Results:

  • Early invasive treatment may benefit high-risk elderly patients with ACS.
  • The role of low-molecular-weight heparin in modern ACS management is under review.
  • Contradictory results exist regarding early intensive lipid-lowering treatment post-ACS.

Conclusions:

  • Evidence supports evaluating early invasive strategies for high-risk elderly ACS patients.
  • Controversies persist regarding low molecular weight heparin and intensive statin regimens in ACS care.
Abstract

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