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Primary colorectal lymphoma in Taiwan
W S Hwang1, J C Yao, S S Cheng
1Department of Internal Medicine, Tri-Service General Hospital, Taipei, Taiwan, Republic of China.
Cancer
|August 1, 1992
Summary
Primary colorectal lymphoma patients in Taiwan were younger and often had T-cell lesions. Surgical resection and chemotherapy offer long-term survival for these patients.
Area of Science:
- Oncology
- Gastroenterology
- Hematology
Background:
- Study of 16 patients with primary lymphoma of the colon and rectum.
- Patients presented with symptoms including abdominal pain, diarrhea, and weight loss.
- Majority of cases were intermediate or high-grade lymphomas, with a notable proportion of T-cell lesions.
Purpose of the Study:
- To investigate the characteristics and outcomes of primary colorectal lymphoma in Taiwan.
- To compare findings with international data on colorectal lymphoma.
- To evaluate the efficacy of surgical resection and chemotherapy.
Main Methods:
- Retrospective analysis of 16 patients diagnosed with primary colorectal lymphoma.
- Diagnostic methods included laparotomy and colonoscopic biopsy.
- Treatment involved surgical resection followed by various chemotherapy regimens (e.g., CHOP, COP).
Main Results:
- Median follow-up was 38 months, with a median survival time of 59 months.
- Eight patients achieved disease-free survival, while six died from the disease.
- One patient succumbed to a secondary esophageal carcinoma.
Conclusions:
- Colorectal lymphoma in Taiwan presents differently, with younger patients and more T-cell lesions compared to other regions.
- Surgical resection combined with adjuvant chemotherapy is effective in achieving long-term survival.
- Despite aggressive histology, favorable outcomes are achievable with appropriate treatment strategies.