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Updated: Aug 3, 2026

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
Published on: September 5, 2011
A case of hypoplastic left heart syndrome and bicuspid aortic valve in monochorionic twins
T S Mu1, R M McAdams, D M Bush
1Wilford Hall Medical Center/859th MDOS, 2200 Bergquist Drive, Suite 1, Lackland AFB, TX 78236-5300, USA. thornton.mu@lackland.af.mil
Abstract:
The etiology of hypoplastic left heart syndrome (HLHS) remains unclear. Since a genetic cause for HLHS has not been obvious, it is generally considered to be inherited in a multifactorial manner. Studies of twins are valuable in elucidating the genetic contribution to a birth defect such as HLHS. We report a case of monochorionic twins in whom one has HLHS and the other has a bicuspid aortic valve. Predisposing genetic and environmental influences on individuals with identical genotypes, such as twins, may result in discordance of left-sided flow lesions.
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