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Related Experiment Videos

Optimal timing for intravenous administration set replacement.

D Gillies1, L O'Riordan, M Wallen

  • 1Sydney West Area Health Service, Locked Bag 7118, Parramatta BC, NSW, Australia 2150. Donna_Gillies@wsahs.nsw.gov.au

The Cochrane Database of Systematic Reviews
|October 20, 2005
PubMed
Summary
This summary is machine-generated.

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Changing intravenous administration sets every 96 hours is safe for non-lipid infusions, reducing infection risk. Current 24-hour replacement for lipid solutions is supported by evidence.

Area of Science:

  • Healthcare management
  • Infection control
  • Intravenous therapy

Background:

  • Intravenous therapy is common in hospitals.
  • Routine replacement of administration sets aims to prevent infusion contamination.
  • Optimizing replacement frequency could lead to significant cost savings.

Purpose of the Study:

  • To determine the optimal interval for routine replacement of intravenous administration sets.
  • To assess replacement intervals for parenteral nutrition (lipid and non-lipid) and other infusions.
  • To evaluate intervals for central and peripheral venous catheters.

Main Methods:

  • Systematic review of randomized and quasi-randomized controlled trials.
  • Searched multiple databases (CENTRAL, MEDLINE, CINAHL, EMBASE) up to February 2004.

Related Experiment Videos

  • Included studies on intravenous administration sets for various infusates and catheter types.

    • Main Results:

    • 13 studies with 4783 participants were analyzed.
    • No evidence shows changing sets more often than every 96 hours reduces bloodstream infections.
    • No significant differences observed between central/peripheral catheters, with/without parenteral nutrition, or in children/adults.

    Conclusions:

    • Intravenous administration sets for non-lipid, non-blood products can remain in place up to 96 hours without increasing infection risk.
    • Evidence supports changing lipid-containing administration sets every 24 hours.
    • Further research is needed to determine optimal intervals for lipid-containing solutions and for changing sets less frequently than 96 hours.