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Updated: Aug 15, 2026

Determination of the Gas-phase Acidities of Oligopeptides
Published on: June 24, 2013
The second acidic constant of salicylic acid
Raffaella Porto1, Gaetano De Tommaso, Emilia Furia
1Dipartimento di Chimica, Università della Calabria, via P. Bucci, Arcavacata di Rende, 87036 Rende (CS), Italy. r.porto@unical.it
Abstract:
The second dissociation constant of salicylic acid (H2L) has been determined, at 25 degrees C, in NaCl ionic media by UV spectrophotometric measurements. The investigated ionic strength values were 0.16, 0.25, 0.50, 1.0, 2.0 and 3.0 M. The protolysis constants calculated at the different ionic strengths yielded, with the Specific Interaction Theory, the infinite dilution constant, log beta1(0) = 13.62 +/- 0.03, for the equilibrium L2- + H+ <==> HL-. The interaction coefficient between Na+ and L2-, b(Na+, L2-) = 0.02 +/- 0.07, has been also calculated.
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