Related Experiment Video

Updated: Aug 15, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
10:08

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

Published on: February 17, 2018

A conceptual model of cognitive deficits in chronic heart failure

Susan J Bennett1, Mary Jane Sauvé, Rose Mary Shaw

  • 1Indiana University School of Nursing, Indianapolis, IN 46202, USA. sbennet@iupui.edu

Journal of Nursing Scholarship : an Official Publication of Sigma Theta Tau International Honor Society of Nursing
|October 21, 2005
PubMed

Insights

This study presents a conceptual model to understand cognitive deficits in heart failure patients. This framework aids in future research and developing interventions for improved quality of life.

Area of Science:

  • Cardiology
  • Neuroscience
  • Psychology

Background:

  • Heart failure (HF) is associated with significant cognitive impairment.
  • Understanding the pathophysiology of HF and cognitive deficits is crucial.
  • Health-related quality of life is a key outcome in HF management.

Purpose of the Study:

  • To propose a conceptual model for studying cognitive deficits in heart failure.
  • To guide empirical research on cognitive dysfunction in HF patients.
  • To inform the development of targeted interventions.

Main Methods:

  • Literature review integrating pathophysiology of heart failure and cognitive deficits.
  • Inclusion of contributing variables such as age, comorbidities, hypertension, and depression.
  • Consideration of covariates like medications, gender, and education.

Main Results:

  • Identified key cognitive domains affected: attention, working memory, memory, learning, executive function, and psychomotor speed.
  • Proposed health-related quality of life as the main outcome variable.
  • Hypothesized influence of circulatory insufficiency and cognitive deficits on quality of life.

Conclusions:

  • The presented model serves as a framework for empirical testing of cognitive deficits in heart failure.
  • Validated through empirical testing, the model can guide intervention development.
  • Aims to improve care for heart failure patients with cognitive complications.
Abstract

More Related Videos

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction09:20

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

Related Concept Videos

Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...