Related Experiment Video
Updated: Aug 15, 2026

JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics
Published on: October 19, 2021
Micro-separation toward systems biology
Bi-Feng Liu1, Bo Xu, Guisen Zhang
1The Key Laboratory of Biomedical Photonics of MOE - Hubei Bioinformatics, Department of Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China. bfliu@mail.hust.edu.cn
Abstract:
Current biology is experiencing transformation in logic or philosophy that forces us to reevaluate the concept of cell, tissue or entire organism as a collection of individual components. Systems biology that aims at understanding biological system at the systems level is an emerging research area, which involves interdisciplinary collaborations of life sciences, computational and mathematical sciences, systems engineering, and analytical technology, etc. For analytical chemistry, developing innovative methods to meet the requirement of systems biology represents new challenges as also opportunities and responsibility. In this review, systems biology-oriented micro-separation technologies are introduced for comprehensive profiling of genome, proteome and metabolome, characterization of biomolecules interaction and single cell analysis such as capillary electrophoresis, ultra-thin layer gel electrophoresis, micro-column liquid chromatography, and their multidimensional combinations, parallel integrations, microfabricated formats, and nano technology involvement. Future challenges and directions are also suggested.
More Related Videos
11:32A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice
Published on: November 23, 2015
07:28Photodegradable Hydrogel Interfaces for Bacteria Screening, Selection, and Isolation
Published on: November 4, 2021
Related Concept Videos
Overview Of Cell Separation And Isolation
Subcellular Fractionation
Differential Centrifugation
Differential centrifugation is...
Modern Molecular Taxonomy
Proteomics
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Evolutionary Relationships through Genome Comparisons
Applications of Molecular Taxonomy