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Cardiogenic hypertrophic osteoarthropathy
1Rheumatology Department, Instituto Nacional de Cardiologia Ignacio Chavez, México D.F.
Insights
Cyanotic congenital heart disease is commonly linked to hypertrophic osteoarthropathy (HOA). Skeletal changes in cardiogenic HOA are more severe and persistent than in other internal illnesses.
Area of Science:
- Cardiology
- Rheumatology
- Pediatric Cardiology
Background:
- Previously, hypertrophic osteoarthropathy (HOA) was considered rare in cyanotic congenital heart disease (CCHD).
- Emerging evidence suggests a significant association between CCHD and HOA.
Purpose of the Study:
- To discuss the clinical features of cardiogenic HOA.
- To highlight the prevalence and severity of HOA in CCHD patients.
Main Methods:
- Review of recent prospective studies on CCHD and HOA.
- Analysis of clinical features and skeletal changes in affected patients.
Main Results:
- Over one-third of patients with CCHD exhibit HOA.
- Skeletal manifestations of cardiogenic HOA are more prevalent, persistent, and severe compared to HOA from other internal diseases.
Conclusions:
- The association between CCHD and HOA is more common than previously thought.
- Cardiogenic HOA presents distinct and severe skeletal changes that warrant clinical attention.
Abstract:
It has been a generally held notion that the association of cyanotic congenital heart diseases with hypertrophic osteoarthropathy (HOA) is exceptional. However, recent prospective studies have demonstrated the opposite to be true. More than a third of patients with cyanotic heart diseases have HOA. The skeletal changes are more prevalent, more persistent and more severe than in any other internal illness. The clinical features of cardiogenic HOA are here discussed.