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Related Experiment Videos

Ventricular function in snorers and patients with obstructive sleep apnea.

P Hanly1, Z Sasson, N Zuberi

  • 1Department of Medicine, Wellesley Hospital, Toronto, Ontario, Canada.

Chest
|July 1, 1992
PubMed
Summary

Obstructive sleep apnea (OSA) does not cause chronic left ventricular dysfunction. Studies found no significant differences in heart function between OSA patients and nonapneic snorers.

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Area of Science:

  • Cardiology
  • Sleep Medicine
  • Pulmonology

Background:

  • Obstructive sleep apnea (OSA) is linked to intermittent hypoxemia and increased ventricular afterload.
  • Chronic left ventricular dysfunction is a potential consequence of these OSA-related physiological changes.

Purpose of the Study:

  • To investigate whether obstructive sleep apnea (OSA) leads to chronic left ventricular dysfunction.
  • To compare cardiac function in patients with and without OSA.

Main Methods:

  • Overnight polysomnography and awake echo-Doppler studies were conducted on 51 snorers (30 with OSA, 21 without).
  • Exclusion criteria included prior myocardial infarction, awake hypoxemia/hypercapnia, or other causes of nocturnal hypoxemia.
  • Left and right ventricular dimensions, wall thickness, systolic performance (e.g., ejection fraction), and diastolic performance were assessed.

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Main Results:

  • Despite OSA patients being heavier and exhibiting higher apnea-hypopnea indices and nocturnal hypoxemia, their cardiac function measurements were within normal limits.
  • No significant differences in echo-Doppler measurements were observed between OSA patients and nonapneic snorers.

Conclusions:

  • Isolated obstructive sleep apnea does not appear to cause chronic left ventricular dysfunction.
  • The study suggests that OSA, in the absence of other confounding factors, does not significantly impair left ventricular function.