Related Experiment Video
Updated: Aug 14, 2026

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
Published on: September 12, 2019
Pretransplant treatments for hepatocellular carcinoma: do they improve outcomes?
1Division of Gastroenterology and Hepatology, Saint Louis University Liver Center, Saint Louis University School of Medicine, St. Louis, MO 63110, USA. dibiscam@slu.edu
Abstract:
1. Locoregional ablative treatments are commonly performed for heptocellular carcinoma (HCC) in patients awaiting transplantation, either to prevent the patient becoming untransplantable due to tumor growth or to prevent tumor recurrence post-operatively. 2. Although these treatments are quite effective at tumor destruction, there is no clear evidence that they improve patient outcomes. 3. Prospective, randomized controlled trials are clearly needed to determine if pre-transplant therapy of HCC is of value.
Related Concept Videos
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure

