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Updated: Jul 30, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
[Anterior cruciate ligament (ACL)]
A Lesić1, M Bumbasirević, S Malobabić
1Institut za ortopedsku hirurgiju i traumatologiju, Klinicki Centar Srbije, Beograd.
Understanding the anterior cruciate ligament (ACL) anatomy is crucial for knee injury treatment. This study details ACL macro- and micro-morphology, vascularization, and innervation for improved therapeutic strategies.
Area of Science:
- Orthopedic surgery
- Sports medicine
- Anatomy
Background:
- The anterior cruciate ligament (ACL) is frequently injured in the knee, often alongside other ligament damage.
- Accurate anatomical knowledge of the ACL is vital for effective clinical management and rehabilitation.
Purpose of the Study:
- To provide a comprehensive description of the anterior cruciate ligament's anatomy.
- To detail the macro- and micro-morphological characteristics, insertions, vascularization, and innervation of the ACL.
Main Methods:
- Review of anatomical literature.
- Macroscopic and microscopic morphological analysis of the ACL.
- Examination of vascular and neural supply.
Main Results:
- Detailed description of ACL macro- and micro-morphology.
- Identification of ACL insertion points.
- Characterization of ACL vascularization and innervation patterns.
Conclusions:
- Comprehensive anatomical understanding of the ACL is essential for advancing knee injury treatment and rehabilitation protocols.
- This detailed anatomical data supports the development of improved therapeutic interventions for ACL injuries.
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