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Myalgia and cramps associated with zolmitriptan
Hortensia Alonso-Navarro1, Félix Javier Jiménez-Jiménez
1Servicio de Neurología, Hospital Universitario San Juan, Alicante, Spain.
Clinical Neuropharmacology
|October 22, 2005
Summary
Zolmitriptan, an antimigraine medication, may cause muscle pain and cramps. These symptoms appear to be dose-dependent, occurring more frequently with higher doses of intranasal zolmitriptan.
Area of Science:
- Neurology
- Pharmacology
Background:
- Migraine is a common neurological disorder.
- Zolmitriptan is a widely used medication for acute migraine treatment.
Observation:
- A 27-year-old woman experienced generalized myalgia and cramps after using intranasal zolmitriptan 5 mg.
- These symptoms were not reported with a lower dose of oral zolmitriptan 2.5 mg.
Findings:
- The patient's symptoms suggest a potential link between zolmitriptan and muscle-related adverse effects.
- Myalgia and cramps may be a dose-dependent side effect of zolmitriptan.
Implications:
- Clinicians should consider myalgia and cramps as potential adverse effects of zolmitriptan.
- Further research may be warranted to investigate the dose-response relationship of zolmitriptan-induced myalgia.