Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

How do retinoblastoma tumours form?

B L Gallie1, J M Dunn, P A Hamel

  • 1Department of Ophthalmology, University of Toronto, Canada.

Eye (London, England)
|January 1, 1992
PubMed
Summary

Understanding retinoblastoma (RB) genetics reveals cancer mechanisms. This knowledge aids new diagnostics and therapies for RB patients, improving treatment outcomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: Impact of disclosure of radiographic test results on quality of life among patients with hernias: a randomized controlled trial.

Hernia : the journal of hernias and abdominal wall surgery·2024
Same author

Impact of disclosure of radiographic test results on quality of life among patients with hernias: a randomized controlled trial.

Hernia : the journal of hernias and abdominal wall surgery·2023
Same author

Characteristics of global naturopathic education, regulation, and practice frameworks: results from an international survey.

BMC complementary medicine and therapies·2021
Same author

DNA hypermethylation/boundary control loss identified in retinoblastomas associated with genetic and epigenetic inactivation of the <i>RB1</i> gene promoter.

Epigenetics·2020
Same author

Endoscopic management of dysplasia and early oesophageal cancer.

Best practice & research. Clinical gastroenterology·2018
Same author

Outcome of the first twenty patients in a Home Parenteral Nutrition (HPN) service at Guys and St. Thomas' Hospital.

Clinical nutrition ESPEN·2017

Area of Science:

  • Ophthalmology
  • Genetics
  • Oncology

Background:

  • Retinoblastoma (RB) is a pediatric eye cancer with complex genetic underpinnings.
  • Previous understanding of RB etiology was limited, hindering targeted treatment development.

Purpose of the Study:

  • To elucidate the genetic causes of retinoblastoma.
  • To explore the implications of genetic discoveries for RB diagnosis and therapy.

Main Methods:

  • Review of current genetic research on retinoblastoma.
  • Analysis of the link between genetic alterations and cancer progression.

Main Results:

  • Significant progress in describing the genetic basis of retinoblastoma.
  • Identification of general cancer development mechanisms through RB studies.

Conclusions:

  • Genetic insights into RB are advancing diagnostic technologies.
  • A genetically informed approach promises novel, less toxic therapies for retinoblastoma.

Related Experiment Videos