Multivalve endocarditis with multiple peripheral and pulmonary embolisms: a case report

Anabela Pinto1, Luísa Moura Branco, Nuno Pelicano

  • 1Serviço de Cardiologia do Hospital de Santa Marta, Lisboa, Portugal. yarispiupiu@iol.pt

Insights

Diagnosing infective endocarditis in elderly patients is challenging. This case highlights the importance of considering this infection, even with atypical presentations like peripheral embolism and mycotic aneurysms.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Geriatrics

Background:

  • Fever of unknown origin (FUO) presents diagnostic challenges in the elderly.
  • Infective endocarditis is frequently overlooked in older patients, with other conditions like cancer often prioritized.
  • Subacute infective endocarditis requires careful consideration in geriatric populations presenting with FUO.

Observation:

  • An elderly woman presented with FUO and was initially suspected of having malignancy.
  • The patient experienced multiple pulmonary and peripheral embolic events.
  • A left femoral mycotic aneurysm was identified during the diagnostic workup.

Findings:

  • The patient was diagnosed with subacute mitral and tricuspid infective endocarditis.
  • Peripheral embolism was a key indicator leading to the correct diagnosis.
  • The presence of a mycotic aneurysm complicated the clinical picture.

Implications:

  • This case underscores the need for a high index of suspicion for infective endocarditis in elderly patients with FUO.
  • Peripheral and pulmonary embolisms can be critical signs of endocarditis in this demographic.
  • Timely diagnosis and treatment of infective endocarditis are crucial to prevent severe complications such as mycotic aneurysms.

Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...