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Related Experiment Videos

[Bat lyssavirus in Thailand].

Boonlert Lumlertdacha1, Supaporn Wacharapluesadee, Lawan Chanhome

  • 1Queen Saovabha Memorial Institute, Thai Red Cross Society, Rama 4 Rd, Bangkok 10330, Thailand. Qsmibld@yahoo.com

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|October 26, 2005
PubMed
Summary

Thai bats surveyed for lyssaviruses showed no rabies virus (RABV) but antibodies to other lyssaviruses, including Australian bat lyssavirus (ABLV), suggesting circulation of novel genotypes.

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Area of Science:

  • Veterinary Virology
  • Wildlife Epidemiology
  • Molecular Biology

Context:

  • Lyssaviruses pose a significant zoonotic threat globally.
  • Bat populations are reservoirs for various lyssavirus genotypes.
  • Previous research on lyssaviruses in Southeast Asian bats is limited.

Purpose:

  • To investigate the prevalence and diversity of lyssavirus infections in Thai bats.
  • To identify specific lyssavirus genotypes circulating in Thailand.
  • To understand the epidemiological significance of lyssaviruses in bat populations.

Summary:

  • A survey of 932 bats from 11 species across Thailand (2001-2003) tested for neutralizing antibodies against rabies virus (RABV), Australian bat lyssavirus (ABLV), and other lyssaviruses.
  • While no RABV antibodies were detected, 16 of 394 bats had antibodies against Irkut, Aravan, Khujand, and ABL viruses; an additional 13 had ABLV antibodies.

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  • The study indicates a lyssavirus prevalence of 7.3% in Thai bats, with antibodies suggesting novel genotypes distinct from previously described ones.

    • Impact:

    • This study reveals the presence of diverse lyssaviruses in Thai bats, potentially including novel genotypes.
    • Findings suggest widespread circulation of several lyssaviruses in Thailand and other Asian countries.
    • Highlights the need for continued surveillance and research into bat-borne lyssaviruses for public health.