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Updated: Aug 15, 2026

Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source
Published on: May 29, 2021
Functional group dependent site specific fragmentation of molecules by low energy electrons
Vaibhav S Prabhudesai1, Aditya H Kelkar, Dhananjay Nandi
1Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai-400005, India.
Abstract:
Functional group dependence is observed in the dissociative electron attachment (DEA) to various organic molecules in which the DEA features seen in the precursor molecules of the groups are retained in the bigger molecules. This functional group dependence is seen to lead to site-selective fragmentation of these molecules at the hydrogen sites. The results are explained in terms of the formation of core-excited Feshbach resonances. The results point to a simple way of controlling chemical reactions as well as interpreting the DEA data from bigger biological molecules.
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