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Off-pump CABG with synchronized arterial flow ensuring system.

Go Watanabe1, Hiroyuki Kamiya, Hiroshi Nagamine

  • 1Department of General and Cardiothoracic Surgery, Kanazawa University School of Medicine, Kanazawa, Japan. go@med.kanazawa-u.ac.jp

The Annals of Thoracic Surgery
|October 26, 2005
PubMed
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A novel synchronized arterial-flow system ensures safe coronary anastomoses during off-pump CABG, preventing ischemia. This innovative approach demonstrated excellent clinical outcomes and high graft patency rates in a large patient cohort.

Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Hemodynamics

Background:

  • Coronary artery bypass grafting (CABG) traditionally involves cardiopulmonary bypass.
  • Off-pump CABG aims to reduce complications associated with cardiopulmonary bypass.
  • Maintaining adequate coronary perfusion during off-pump CABG remains a challenge.

Purpose of the Study:

  • To introduce and evaluate a synchronized arterial-flow ensuring system for coronary anastomoses.
  • To assess the safety and efficacy of this system in preventing ischemia-related events during off-pump CABG.
  • To report early clinical and angiographical outcomes.

Main Methods:

  • Arterial blood is sourced from the femoral artery and pumped using a syringe pump.
  • Blood flow is pulsatile and synchronized with the electrocardiogram's diastolic phase.

Related Experiment Videos

  • The system delivers synchronized arterial blood flow to the coronary artery via a cannula during anastomosis.

    • Main Results:

    • 524 consecutive patients underwent off-pump CABG using the system.
    • Mean anastomosis time was 7.6 ± 3.3 minutes.
    • No intraoperative arrhythmias, hemodynamic deterioration, or hospital deaths occurred.
    • Postoperative myocardial infarction rate was 0.4% (2 patients).
    • Angiography revealed a 98.1% graft patency rate.

    Conclusions:

    • The synchronized arterial-flow ensuring system facilitates safe off-pump CABG.
    • Excellent early clinical and angiographical results, including no mortality, were achieved.
    • This system enhances the safety profile of off-pump CABG procedures.