Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Progressive supranuclear palsy: a systematic review.

L Rampello1, V Buttà, R Raffaele

  • 1Department of Neurosciences, University of Catania, Azienda Policlinico-Neurologia, via S. Sofia, 78, 95125 Catania, Italy. rampello@unict.it

Neurobiology of Disease
|October 26, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Decoding the Conformation of Polylactic Acid in Block Copolymer Micelles.

Journal of the American Chemical Society·2026
Same author

Popularity of heated-tobacco products and e-cigarettes among medical school students in Rome, Italy: factors associated with use and attitudes towards quitting.

La Clinica terapeutica·2025
Same author

Deviations from the Porter-Thomas Distribution due to Nonstatistical γ Decay below the ^{150}Nd Neutron Separation Threshold.

Physical review letters·2025
Same author

Characterisation of functional deficits induced by AAV overexpression of alpha-synuclein in rats.

Current research in neurobiology·2023
Same author

Thiol-Functionalized Block Copolymer Vesicles.

ACS macro letters·2022
Same author

E-learning course improves knowledge in tobacco dependence, electronic nicotine delivery systems and heat-not-burn products in Medical School students.

La Clinica terapeutica·2021

Progressive supranuclear palsy (PSP) is a rapid tauopathy affecting brain structures. Research reviews genetic, environmental, and oxidative factors contributing to tau deposition and neuronal pathway dysfunction in PSP.

Area of Science:

  • Neuroscience
  • Neurology
  • Pathology

Background:

  • Progressive supranuclear palsy (PSP) is a rapidly progressing tauopathy.
  • It involves both cortical and subcortical brain structures.
  • The exact pathogenesis of PSP remains uncertain.

Purpose of the Study:

  • To review current understanding of PSP pathogenesis.
  • To explore contributing factors to tau deposition and neuronal dysfunction.
  • To highlight advances in diagnosis and pathophysiology insights.

Main Methods:

  • Review of genetic studies.
  • Review of biochemical studies.
  • Review of immunohistochemical studies.

Main Results:

Related Experiment Videos

  • Genetic, oxidative, neurotoxic, and environmental factors contribute to tau deposition in PSP.
  • Dysfunction of dopaminergic, GABAergic, cholinergic, and noradrenergic pathways leads to symptoms.
  • Advances in neuroradiology and instrumental examinations aid diagnosis and understanding.

Conclusions:

  • The primary cause of PSP is unknown.
  • Disease-modifying drugs for PSP are not yet available.
  • Further research is needed to elucidate PSP's etiology and develop treatments.