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Published on: September 12, 2019
Guillain-Barre syndrome occurring after adjuvant chemo-radiotherapy for endometrial cancer
L M Tho1, C P O'Leary, I Horrocks
1Department of Clinical Oncology, Beatson Oncology Centre, Dumbarton Road, Glasgow G11 6NT, UK. Lye.Mun.Tho@NorthGlasgow.Scot.NHS.UK
Background:
The association between Guillain-Barre syndrome (GBS) and malignancy is uncommon and has not been previously reported in gynecological cancers.
Case:
Our case documents this syndrome occurring in a patient shortly after completion of adjuvant chemo-radiotherapy for endometrial carcinoma. We review the current literature and discuss potential pathogenic mechanisms of this likely paraneoplastic association.
Conclusion:
GBS in cancer patients is a potentially life-threatening condition and should be differentiated from simple chemotherapy toxicity, particularly as effective treatment is available.
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