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Published on: August 15, 2025
Peripheral primitive neuroectodermal tumor associated with the anterior mandible: a case report and review of the
Timothy J Votta1, Joseph J Fantuzzo, Barry C Boyd
1Department of Oral And Maxillofacial Surgery, State University of New York-Buffalo School of Dental Medicine, Buffalo, NY 14214-3008, USA. tvotta@buffalo.edu
Abstract:
Neuroectodermal tumors may arise in many places throughout the body including the diverse tissues of the head and neck. The primitive neuroectodermal tumor is a predominately neural, nonepithelial neoplasm similar to Ewing sarcoma. This article describes an 18-year-old female patient with a highly malignant peripheral primitive neuroectodermal tumor located in the soft tissue anterior to the mandibular symphysis. The clinical and radiographic presentation as well as the histopathology and immunohistochemistry of this rare entity is discussed. A review of the literature with respect to this tumor, as well as the current management of this tumor, is presented.