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Cholangiohepatitis in a dog
S D Forrester1, K S Rogers, R L Relford
1Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg 24061-0442.
Summary
Cholangiohepatitis in dogs is uncommon but should be suspected in cases of anorexia, vomiting, fever, and jaundice. Bacterial cultures of liver and bile are crucial for diagnosis, and antibiotic treatment can resolve clinical signs.
Area of Science:
- Veterinary Medicine
- Canine Infectious Diseases
Background:
- Cholangiohepatitis is an inflammation of the bile ducts and liver in dogs.
- It is considered an uncommon condition in canine medicine.
Observation:
- A dog presented with anorexia, vomiting, fever, and icterus, indicating severe illness.
- Clinical signs included depression, dehydration, enlarged liver and spleen, and abdominal discomfort.
Findings:
- Histologic examination revealed acute, suppurative cholangiohepatitis and splenitis.
- Bacterial cultures of liver and bile identified Klebsiella sp. as the causative agent.
Implications:
- Early suspicion of cholangiohepatitis is vital in dogs exhibiting anorexia, fever, vomiting, icterus, and abdominal pain.
- Definitive diagnosis relies on bacterial cultures of liver and bile specimens.
- Prompt antibiotic therapy, such as chloramphenicol, alongside supportive care, can lead to successful resolution of clinical signs.