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Opposing actions of STAT-1 and STAT-3

A Stephanou1, D S Latchman

  • 1Institute of Child Health, University College London, Medical Molecular Biology Unit, London, UK. a.stephanou@ich.ucl.ac.uk

Growth Factors (Chur, Switzerland)
|October 26, 2005
PubMed
Summary

Signal transducers and activators of transcription (STATs) like STAT-1 and STAT-3 have opposing roles in cell death and growth. These transcription factors regulate gene expression through DNA binding and co-activator mechanisms, impacting proliferation and apoptosis differently.

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