Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The vertical wedge biopsy.

D A Gross

    The Journal of Dermatologic Surgery and Oncology
    |July 1, 1992
    PubMed
    Summary
    This summary is machine-generated.

    A simple, cost-effective scalpel blade biopsy technique provides sufficient tissue for diagnosis without disrupting tumor margins. This method preserves therapeutic options, but requires careful selection of skin lesions for optimal results.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Muscle-specific, liver-detargeted adeno-associated virus gene therapy rescues Pompe phenotype in adult and neonate Gaa<sup>-/-</sup> mice.

    Journal of inherited metabolic disease·2023
    Same author

    Induction of tumor-specific CTL responses using the C-terminal fragment of Viral protein R as cell penetrating peptide.

    Scientific reports·2019
    Same author

    HLA-A*0201-restricted cytolytic responses to the rtTA transactivator dominant and cryptic epitopes compromise transgene expression induced by the tetracycline on system.

    Molecular therapy : the journal of the American Society of Gene Therapy·2004
    Same author

    [Anchoring cytokines to cancer cells using diphtheria toxin: better than immunotherapy by gene transfer?].

    Journal de la Societe de biologie·2002
    Same author

    Identification of HER-2/neu immunogenic epitopes presented by renal cell carcinoma and other human epithelial tumors.

    European journal of immunology·2001
    Same author

    A skin surgery fable.

    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2001
    Same journal

    Malignant fibrous histiocytoma at the site of total knee replacement.

    The Journal of dermatologic surgery and oncology·1994
    Same journal

    Basal cell carcinoma arising in a surgical scar: reconstructive surgical treatment.

    The Journal of dermatologic surgery and oncology·1994
    Same journal

    The use of hyaluronidase as an adjunct to surgical procedures.

    The Journal of dermatologic surgery and oncology·1994
    Same journal

    Repair of the soft triangle of the nose.

    The Journal of dermatologic surgery and oncology·1994
    Same journal

    Eccrine angiomatous hamartoma.

    The Journal of dermatologic surgery and oncology·1994
    Same journal

    Treatment of pyoderma gangrenosum with cultured keratinocyte autografts.

    The Journal of dermatologic surgery and oncology·1994
    See all related articles

    Area of Science:

    • Dermatology
    • Surgical Pathology

    Background:

    • Accurate tissue diagnosis is crucial for effective treatment planning.
    • Traditional biopsy methods can sometimes disrupt tumor margins, complicating subsequent therapeutic choices.

    Purpose of the Study:

    • To describe a simple, cost-effective biopsy technique using a scalpel blade.
    • To highlight the benefits of this technique in preserving tumor margins for accurate diagnosis and treatment planning.

    Main Methods:

    • A single surgical tool, the scalpel blade, is utilized.
    • The technique involves careful lesion selection, excluding suspected malignant melanoma or deep dermatoses.

    Main Results:

    • The technique consistently yields sufficient tissue for histologic analysis.

    Related Experiment Videos

  • Preservation of tumor margins allows for unimpeded diagnostic and therapeutic decision-making.
  • Conclusions:

    • This scalpel blade biopsy method is a practical and economical approach for obtaining diagnostic tissue.
    • Appropriate patient selection is paramount for the successful application of this biopsy technique.