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Updated: Aug 15, 2026

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
Ovarian cancer, diagnosed with PET, with bilateral inguinal lymphadenopathy as primary presenting sign
Natalina Manci1, Filippo Bellati, Marialida Graziano
1Institute of Gynecology, Perinatology and Child Health, University La Sapienza di Roma, Viale Regina Elena 324, 00161 Rome, Italy. n.manci@unicampus.it
Background:
Ovarian cancer groin lymph nodes metastases are rare. Only one case of disease spread isolated to the groins has been reported in the English literature. We report the case of a patient with bilateral inguinal lymphadenopathy due to tumor metastases and in which tumor origin was diagnosed using [(18)F]fluorodeoxyglucose positron emission tomography (PET).
Case Report:
This is the first case of bilateral groin lymph nodes as sole site of metastases from ovarian cancer. Primary origin was identified using PET.
Conclusions:
In rare cases, the ovaries can directly metastasis to the groin even in a relatively initial tumor growth phase. PET may play a role in the diagnosis of occult ovarian tumors.
