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Developing a sustainable process to provide quality control materials for genetic testing.

Bin Chen1, Catherine D O' Connell, D Joe Boone

  • 1Quality Control Materials for Genetic Testing Group, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.

Genetics in Medicine : Official Journal of the American College of Medical Genetics
|October 26, 2005
PubMed
Summary

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This summary is machine-generated.

Ensuring access to quality control (QC) materials is vital for reliable genetic testing. The Centers for Disease Control and Prevention (CDC) established a program to improve QC material availability for molecular genetic tests.

Area of Science:

  • Clinical Diagnostics
  • Molecular Genetics
  • Quality Assurance

Background:

  • Genetic testing quality control (QC) materials are essential for accurate diagnostics.
  • Current availability of QC materials for genetic tests is insufficient.
  • Conferences convened experts to address this gap.

Framework:

  • Recommendations focused on sustainable mechanisms for QC material provision.
  • Emphasis on molecular genetic testing as an initial step.
  • Workgroups identified key issues and areas of need.

Implementation:

  • The Centers for Disease Control and Prevention (CDC) organized expert working conferences.
  • Participants represented diverse sectors of the genetic testing community.
  • Review of current QC material development efforts informed recommendations.

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Implications:

  • Improved QC materials enhance genetic testing quality and performance evaluation.
  • Better QC supports proficiency testing (PT) and external quality assessment (EQA) programs.
  • A new CDC Genetic Testing Quality Control Materials Program was established in March 2005.