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Propynyl groups in duplex, hairpin and triplex DNA: 7-deazapurines and 9-deazapurines
Frank Seela1, Khalil I Shaikh, Simone Budow
1Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universität Osnabrück, Germany.
Nucleosides, Nucleotides & Nucleic Acids
|October 27, 2005
Abstract:
Oligonucleotides containing 7-deazapurines or 9-deazapurines with propynyl groups at the 7- or 9-position were prepared. The stabilizing effect of the propynyl group was studied on DNA duplexes, hairpins and triplexes.
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