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Affinity of (alpha-P-borano)-NTP analogs to rabbit muscle pyruvate kinase

Mikhail I Dobrikov1, Barbara Ramsay Shaw

  • 1Department of Chemistry, P.M. Gross Chemical Laboratory, Duke University, Durham, NC 27705, USA.

Nucleosides, Nucleotides & Nucleic Acids
|October 27, 2005
PubMed

Abstract:

The binding affinity of (alpha-P-borano) and other NTP analogs to rabbit muscle pyruvate kinase (PK) was investigated using a fluorescence quenching approach to obtain structure-activity relationships for substrate specificity of nucleotide analogs.

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