["Can high fluid intake prevent cerebral and myocardial infarction?" Systematic review]

Kikuo Okamura1, Yukihiko Washimi, Hidetoshi Endo

  • 1Department of Urology, National Center Hospital for Geriatrics and Gerontology.

Insights

High fluid intake may help reduce blood viscosity, a factor in cerebral and myocardial infarction. However, current evidence does not confirm that increased water consumption prevents these ischemic events.

Area of Science:

  • Cardiovascular Science
  • Neurology
  • Public Health

Background:

  • Cerebral and myocardial infarction are significant causes of morbidity and mortality.
  • Atherosclerosis and atheroma plaque are primary etiological factors.
  • Blood viscosity and dehydration are implicated as contributing factors.

Purpose of the Study:

  • To systematically review the evidence on whether high fluid intake can prevent cerebral and myocardial infarction.
  • To explore the relationship between fluid intake, blood viscosity, and ischemic events.

Main Methods:

  • Systematic review of previously published papers.
  • Searched PubMed using keywords related to dehydration, hydration, fluid intake, cerebral infarction, myocardial infarction, blood viscosity, and hemorheology.
  • Included 22 selected studies of various designs (randomized, non-randomized, epidemiologic, retrospective).

Main Results:

  • Dehydration increases blood viscosity, a potential cause of cerebral or myocardial infarction.
  • Factors other than dehydration can also increase blood viscosity.
  • No direct evidence shows high fluid intake prevents cerebral infarction, though night-time drinking may reduce viscosity.
  • One report suggested a lower myocardial infarction risk in individuals drinking >5 glasses of water daily compared to <2.

Conclusions:

  • Lifestyle adjustments are crucial for preventing cerebral and myocardial infarction due to underlying atherosclerosis.
  • Direct evidence linking high fluid intake to prevention of cerebral infarction via viscosity reduction is lacking.
  • Further research is needed on fluid intake and ischemic diseases, especially for the elderly to enhance quality of life.
Abstract

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