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Related Experiment Videos

Reversal of digital vasospasm by glyceryl trinitrate patch.

R A Evans1, P L Sanderson, J K Stanley

  • 1Department of Hand Surgery, Wrightington Hospital, Lancashire.

Journal of Hand Surgery (Edinburgh, Scotland)
|June 1, 1992
PubMed
Summary

Localized digital ischemia after tourniquet deflation can occur post-hand surgery. A topical glyceryl trinitrate patch effectively restored circulation in three cases, offering a potential therapeutic and diagnostic aid.

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Area of Science:

  • Hand Surgery
  • Vascular Surgery
  • Dermatology

Background:

  • Digital ischemia post-tourniquet deflation is a concern in hand surgery, especially after correcting severe deformities.
  • Prompt recognition and management are crucial to prevent complications.

Observation:

  • Three cases of immediate digital ischemia after releasing severe flexion contractures are presented.
  • The affected digits showed impaired circulation upon tourniquet release.

Findings:

  • Application of a proximal cutaneous glyceryl trinitrate patch led to rapid circulatory recovery in all three cases.
  • Glyceryl trinitrate facilitated prompt restoration of blood flow to the ischemic digits.

Implications:

  • Topical glyceryl trinitrate presents a simple, effective therapeutic option for post-operative digital ischemia.

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  • This treatment may serve as a valuable diagnostic aid, potentially avoiding surgical re-exploration.