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[Uveitis and chronic intestinal inflammatory diseases: three case studies].
Z Chaoui1, A Bernoussi, M Belmekki
1Service d'Ophtalmologie B, Hôpital des spécialités, CHU Rabat, Maroc.
Journal Francais D'Ophtalmologie
|October 27, 2005
Summary
Anterior uveitis is a common ocular issue in inflammatory bowel diseases like Crohn disease and ulcerative colitis. Treatment involves anti-inflammatory agents, with surgery sometimes needed for severe cases.
Area of Science:
- Ophthalmology
- Gastroenterology
- Immunology
Background:
- Inflammatory bowel diseases (IBD), including Crohn disease and ulcerative colitis, frequently cause extra-intestinal manifestations.
- Anterior uveitis is the most common ocular complication, presenting as an exclusively inflammatory process.
Observation:
- This report details three cases of bilateral uveitis associated with IBD (two ulcerative colitis, one Crohn disease).
- Uveitis onset varied, occurring years after IBD diagnosis or following bowel surgery, and sometimes coinciding with IBD relapses.
Findings:
- Topical corticosteroids were effective in two cases without recurrence.
- The third case required both topical and systemic corticosteroids, but developed complications including inflammatory glaucoma necessitating surgery.
Implications:
- Anterior uveitis affects approximately 1.9-4.9% of Crohn disease patients and 1.6% of ulcerative colitis patients.
- The course of uveitis often mirrors IBD activity, requiring anti-inflammatory treatment.
- Severe or refractory cases may necessitate surgical intervention for ocular complications or bowel resection for disease control.