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Polymyalgia rheumatica and colon malignacy: case report

Tatjana Kehler1, Bozidar Curković

  • 1Hospital for Cardial, Pulmonal and Rheumatic Rehabilitation, Talassotherapia, Opatija, Croatia.

Clinical Rheumatology
|October 27, 2005
PubMed

Insights

Polymyalgia rheumatica (PMR) is common in older adults. This case study explores a potential paraneoplastic link between PMR and sigmoid colon adenocarcinoma, suggesting malignancy may trigger inflammatory symptoms.

Area of Science:

  • Rheumatology
  • Oncology
  • Clinical Medicine

Background:

  • Polymyalgia rheumatica (PMR) is a prevalent inflammatory condition in the elderly.
  • The association between PMR and giant cell arteritis (GCA) is established.
  • A controversial link between PMR and underlying malignancy remains under investigation.

Observation:

  • A case of polymyalgia rheumatica (PMR) is presented in conjunction with sigmoid colon adenocarcinoma.
  • This presentation suggests a potential paraneoplastic syndrome.

Findings:

  • The study hypothesizes a paraneoplastic relationship between PMR and sigmoid colon cancer.
  • This hypothesis posits that the malignancy may be inducing the inflammatory symptoms characteristic of PMR.

Implications:

  • Recognizing a potential paraneoplastic link could improve diagnostic pathways for PMR patients.
  • Further research into the association between PMR and malignancy is warranted.
  • This case highlights the importance of considering occult malignancies in elderly patients presenting with PMR.

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