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Aneurysm recurrence following endovascular balloon occlusion
C B Heilman1, E S Kwan, J K Wu
1Department of Neurosurgery, Tufts University School of Medicine, Boston, Massachusetts.
Journal of Neurosurgery
|August 1, 1992
Summary
Endovascular balloon occlusion for cerebral aneurysms showed high recurrence rates. Latex balloons induced a better fibrotic response than silicone balloons, but neither prevented recurrence, necessitating follow-up angiography.
Area of Science:
- Neurosurgery
- Vascular Surgery
- Medical Devices
Background:
- Cerebral aneurysms pose significant risks, and endovascular treatments offer alternatives for surgically inaccessible cases.
- Endovascular balloon occlusion is one such technique, but its long-term efficacy requires further investigation.
Purpose of the Study:
- To compare the efficacy of silicone versus latex balloons in endovascular occlusion of cerebral aneurysms.
- To assess the recurrence rates and tissue response associated with different balloon materials.
Main Methods:
- Aneurysm models were created in rabbits and treated with either silicone or latex balloons via endovascular occlusion.
- Control groups were established, and aneurysm recurrence and tissue response were evaluated at 3 months post-procedure.
Main Results:
- A high recurrence rate (90%) was observed in balloon-occluded aneurysms at 3 months.
- Recurrent aneurysms were larger when treated with silicone balloons compared to latex balloons.
- Latex balloons induced a significant fibrotic response, unlike silicone balloons.
Conclusions:
- Current endovascular balloon occlusion techniques have high recurrence rates for cerebral aneurysms.
- The choice of balloon material may influence recurrence size and tissue response, but does not eliminate recurrence.
- Periodic follow-up angiography is crucial after endovascular balloon occlusion to monitor for aneurysm recurrence.