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Updated: Aug 15, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Neonatal meliodosis: very rare but be aware
1Paediatric Unit, Hospital Tengku Ampuan Afzan, Jalan Tanah Putih, 25100 Kuantan, Pahang.
Abstract:
Meliodosis is an infectious disease encountered mainly in tropics. It is not an uncommon problem in Malaysia especially in areas with agricultural activities. Although it can occur in all age groups, there have been few reported cases in children. Men are more commonly affected than women due to outdoor activities. Neonatal cases have been reported in Hawaii and Thailand. These infants presented with neonatal sepsis or meningitis. The mode of transmission to these infants has not been elucidated. This is the report of such a case first reported in Hospital Tengku Ampun Afzan, Kuantan.
Insights
Melioidosis, a tropical infectious disease, is uncommon in Malaysian children. This report details the first neonatal case of melioidosis in Kuantan, Malaysia, highlighting a rare presentation of this bacterial infection.
Area of Science:
- Tropical infectious diseases
- Pediatric infectious diseases
- Bacteriology
Background:
- Melioidosis is an infectious disease prevalent in tropical regions, particularly in agricultural areas of Malaysia.
- While occurring across all age groups, pediatric melioidosis cases are infrequently reported.
- Male predominance is noted, likely due to increased outdoor occupational exposure.
Observation:
- Neonatal melioidosis, presenting as sepsis or meningitis, has been documented in Thailand and Hawaii.
- The transmission route of melioidosis to neonates remains largely unelucidated.
- This report documents the first neonatal case of melioidosis diagnosed at Hospital Tengku Ampun Afzan in Kuantan, Malaysia.
Findings:
- This case represents a rare instance of neonatal melioidosis in Malaysia.
- The clinical presentation in this neonate warrants further investigation into transmission pathways.
- This report contributes to the limited literature on pediatric melioidosis.
Implications:
- Increased awareness of neonatal melioidosis is crucial for early diagnosis and treatment in endemic areas.
- Further research is needed to understand the specific modes of transmission to infants.
- This case highlights the importance of considering melioidosis in neonates presenting with sepsis or meningitis in tropical regions.
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