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Naturally-occurring xanthones: recent developments.

L M M Vieira1, A Kijjoa

  • 1ICBAS--Instituto de Ciencias Biomédicas de Abel Salazar, Universidade do Porto, Largo Prof. Abel Salazar, 2, 4099-003, Porto, Portugal.

Current Medicinal Chemistry
|October 28, 2005
PubMed
Summary
This summary is machine-generated.

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This review details 515 naturally occurring xanthones reported between 2000-2004, including 278 novel compounds. These xanthones were identified from diverse plant, fungal, and lichen sources, with structural and biological data provided.

Area of Science:

  • Natural Product Chemistry
  • Phytochemistry
  • Mycology

Background:

  • Xanthones are a significant class of natural products with diverse biological activities.
  • Previous literature reviews have cataloged xanthone discoveries, but a comprehensive update is needed.

Purpose of the Study:

  • To present a comprehensive literature survey of naturally occurring xanthones reported from January 2000 to December 2004.
  • To document newly identified xanthones and their sources.

Main Methods:

  • Literature search of scientific databases and journals.
  • Compilation and analysis of reported xanthone structures and sources.
  • Inclusion of structural formulas, distribution, and biological properties.

Main Results:

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  • A total of 515 xanthones were reported during the survey period.
  • 278 of these reported xanthones were identified as new natural compounds.
  • These xanthones were isolated from 20 families of higher plants, fungi, and lichens.

Conclusions:

  • The period 2000-2004 saw a significant increase in the discovery of natural xanthones.
  • The diverse botanical and mycological origins highlight the potential for further xanthone exploration.
  • This review serves as a valuable resource for researchers in natural product chemistry.