Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Xanthones--a structural perspective.

L Gales1, A M Damas

  • 1ICBAS-Instituto de Ciencias Biomédicas Abel Salazar & IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal.

Current Medicinal Chemistry
|October 28, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Eosinophilic annular erythema effectively treated with dupilumab.

Annales de dermatologie et de venereologie·2026
Same author

Repression of oxidative phosphorylation by NR2F2, MTERF3 and GDF15 in human skin under high-glucose stress.

Redox biology·2025
Same author

Microrheological characterisation of Cyanoflan in human blood plasma.

Carbohydrate polymers·2023
Same author

Mixing and matching methylotrophic enzymes to design a novel methanol utilization pathway in E. coli.

Metabolic engineering·2020
Same author

Hydrophobic dipeptide crystals: a promising Ag-free class of ultramicroporous materials showing argon/oxygen adsorption selectivity.

Physical chemistry chemical physics : PCCP·2014
Same author

Keratins and lipids in ethnic hair.

International journal of cosmetic science·2013

Xanthones, natural compounds with diverse biological activities, are being studied using 3D structural data from X-ray diffraction. This research aims to clarify their molecular mechanisms and enhance understanding of their pharmacological effects.

Area of Science:

  • Medicinal Chemistry
  • Structural Biology
  • Pharmacology

Background:

  • Xanthones are a class of compounds found in nature and synthesized in labs.
  • They exhibit significant biological and pharmacological properties.
  • Their chemical structures are crucial for understanding their activities.

Purpose of the Study:

  • To review and analyze the 3D structural data of xanthones obtained through single crystal X-ray diffraction.
  • To correlate structural information with biological activities.
  • To deepen the understanding of molecular mechanisms underlying xanthone functions.

Main Methods:

  • Literature review focusing on studies utilizing single crystal X-ray diffraction for xanthone structure elucidation.
  • Analysis of reported 3D structural data of various xanthones.

Related Experiment Videos

  • Correlation of structural features with documented biological activities.

    • Main Results:

    • Compilation of 3D structural data for a range of xanthones.
    • Identification of key structural motifs associated with specific biological activities.
    • Insights into how molecular conformation influences pharmacological effects.

    Conclusions:

    • Three-dimensional structural data from X-ray diffraction is vital for understanding xanthone bioactivity.
    • This structural information provides a foundation for designing novel xanthone-based therapeutics.
    • Further investigation into structure-activity relationships will unlock the full potential of xanthones.