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Contralateral renal abnormalities in multicystic-dysplastic kidney disease
1Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75235-9063.
The Journal of Pediatrics
|July 1, 1992
Summary
Multicystic-dysplastic kidney (MCDK) disease frequently co-occurs with other urologic issues. Contralateral vesicoureteral reflux is the most common associated abnormality in children with MCDK.
Area of Science:
- Pediatric Nephrology
- Urology
- Medical Imaging
Background:
- Multicystic-dysplastic kidney (MCDK) disease is a congenital condition.
- Associated genitourinary tract abnormalities are known but not fully characterized.
- The nature and prevalence of contralateral renal lesions in MCDK require delineation.
Purpose of the Study:
- To determine the prevalence of contralateral renal abnormalities in patients with MCDK.
- To identify other urologic anomalies associated with MCDK.
- To characterize the specific types of genitourinary abnormalities found.
Main Methods:
- Retrospective study of 49 patients aged 0-6 years with MCDK.
- Utilized renal ultrasonography, excretory urography, nuclear medicine scanning, and voiding cystourethrography.
- Analyzed the location and type of associated urologic abnormalities.
Main Results:
- 51% of patients with MCDK had an associated urologic abnormality.
- Contralateral abnormalities were present in 39% of patients.
- Vesicoureteral reflux (18%) and ureteropelvic junction obstruction (12%) were the most common contralateral findings.
Conclusions:
- Urologic anomalies are common in children with MCDK.
- Contralateral vesicoureteral reflux is the most frequent associated genitourinary abnormality.
- Early detection and management of these anomalies are crucial.