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Contralateral renal abnormalities in multicystic-dysplastic kidney disease

B Atiyeh1, D Husmann, M Baum

  • 1Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75235-9063.

The Journal of Pediatrics
|July 1, 1992
PubMed

Insights

Multicystic-dysplastic kidney (MCDK) disease frequently co-occurs with other urologic issues. Contralateral vesicoureteral reflux is the most common associated abnormality in children with MCDK.

Area of Science:

  • Pediatric Nephrology
  • Urology
  • Medical Imaging

Background:

  • Multicystic-dysplastic kidney (MCDK) disease is a congenital condition.
  • Associated genitourinary tract abnormalities are known but not fully characterized.
  • The nature and prevalence of contralateral renal lesions in MCDK require delineation.

Purpose of the Study:

  • To determine the prevalence of contralateral renal abnormalities in patients with MCDK.
  • To identify other urologic anomalies associated with MCDK.
  • To characterize the specific types of genitourinary abnormalities found.

Main Methods:

  • Retrospective study of 49 patients aged 0-6 years with MCDK.
  • Utilized renal ultrasonography, excretory urography, nuclear medicine scanning, and voiding cystourethrography.
  • Analyzed the location and type of associated urologic abnormalities.

Main Results:

  • 51% of patients with MCDK had an associated urologic abnormality.
  • Contralateral abnormalities were present in 39% of patients.
  • Vesicoureteral reflux (18%) and ureteropelvic junction obstruction (12%) were the most common contralateral findings.

Conclusions:

  • Urologic anomalies are common in children with MCDK.
  • Contralateral vesicoureteral reflux is the most frequent associated genitourinary abnormality.
  • Early detection and management of these anomalies are crucial.

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