Related Experiment Video
Updated: Aug 15, 2026

11:04
An In-House-Built and Light-Emitting-Diode-Based Photodynamic Therapy Device for Enhancing Verteporfin Cytotoxicity in a 2D Cell Culture Model
Published on: January 13, 2023
Nonlinear photodynamic therapy: method of pulsed oxygen depletion
1Organic Intermediates and Dyes Institute, B. Sadovaya str. 1/4, 123995 Moscow, Russia. bkogan@mail.mipt.ru
Abstract:
The photodynamic therapy technique involving pulsed oxygen depletion (POD) in tissue by long high-energy pulses of light was studied theoretically. The possibility of creating a uniform distribution of a therapeutic dose throughout a tumor using both surface and interstitial irradiation is shown. Possible thickness of the treated tissue layer is estimated. The comparison with other methods of nonlinear photodynamic therapy is made.

