Cytotoxic phenylpropanoid glycosides from the stems of Smilax china
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Yao-Haur Kuo1, Ya-Wen Hsu, Chia-Ching Liaw
1National Research Institute of Chinese Medicine, Taipei, 112 Taiwan, Republic of China. kuoyh@nricm.edu.tw
Journal of Natural Products
|October 29, 2005
Abstract:
Bioassay-guided fractionation of an ethanol extract of Smilax china led to the isolation of nine phenylpropanoids including six new compounds, smilasides A-F (1-6), and three known phenylpropanoids, smiglaside E, heloniosides B, and 2',6'-diacetyl-3,6-diferuloylsucrose. Structural elucidation of isolates 1-6 was based on spectroscopic data analysis. These new phenylpropanoids were evaluated against several human tumor cell lines.