Related Experiment Video
Updated: Aug 15, 2026
Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
Published on: April 21, 2022
Recognition of histopathologic patterns of diffuse malignant mesothelioma in differential diagnosis of pleural
1Department of Pathology, The University of Texas Health Center, Tyler, TX 75708, USA. timothy.allen@uthct.edu
Context:
Diffuse malignant mesothelioma is generally divided into 3 basic histologic types--epithelial, biphasic, or sarcomatous. However, a great diversity of histologic patterns exists within these 3 basic histologic types.
Design:
The diverse histologic patterns of diffuse malignant mesothelioma are briefly described, including infrequently encountered patterns.
Results:
The histologic patterns of diffuse malignant mesothelioma provide a wide variation of features for the pathologist to consider in the differential diagnosis of a pleural biopsy.
Conclusion:
Pathologists should be aware of the varied histologic patterns of diffuse malignant mesothelioma when evaluating pleural biopsies.
